产品货号：
Z12639
中文名称：
CD1A抗体
英文名称：
Anti-CD1A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD1A Antibody |
| 指标别名 | CD1;CD1A;CD1a molecule;FCB6;HTA1;hTa1 thymocyte antigen;R4;T6 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC |
| 基因名称 | CD1A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human CD1a(158-173aa AKHFCKVLNQNQHEND). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CD1A(Thymocyte antigen CD1A) also known as CD1,is a human protein encoded by the°CD1A gene.CD1A is 1 of 5 distinct CD1 genes that are variably conserved in different mammalian species.This gene encodes a member of the CD1 family of transmembrane glycoproteins,which are structurally related to the major histocompatibility complex(MHC) proteins and form heterodimers with beta-2-microglobulin.The CD1A gene is mapped on 1q23.1.The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.°CD1A is concentrated in the early or recycling endosome.Moody et al.(2004) reported that°CD1A presents to T cells a family of previously unknown lipopeptides from Mycobacterium tuberculosis,named didehydroxymycobactins because of their structural relation to mycobactin siderophores.The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system.Apolipoprotein E(107741) binds lipid antigens and delivers them by receptor-mediated uptake into endosomal compartments containing CD1 in antigen-presenting cells. |
| Uniprot ID | P06126 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | CD1a molecule |
| 蛋白名全称 | T-cell surface glycoprotein CD1a |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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